Surgery Godfather
Chapter 858 - 763: The Shining New Star

Chapter 858: Chapter 763: The Shining New Star

Claus sought Yang Ping’s assistance and was therefore very open with him, detailing the entire experimental process.

The breakthrough in Mayo’s eye transplantation animal experiments confirmed Yang Ping’s belief that gene control must lie behind cell behavior, with genes orchestrating everything.

The astute Mayo Doctor discovered differences between two types of mice and traced the problems back to those differences.

In his experiments, Yang Ping used normal stem cells, tumor cells, and teratoma cells to establish three models, hoping to find the differences between them and identify the genetic variations that might be the key to unlocking the mysteries.

Once the gene segments were identified, and methods to activate or block them were found, the problem would naturally be solved.

Yang Ping helped them perform ten syngeneic heterotopic eye transplantation surgeries on mice, ensuring high-quality vascular and nerve anastomosis to maximize the success of the experiment.

The arteriole of a mouse’s eye is quite small, and the anastomosis technique under American microscopes clearly falls behind that of China, which is recognized as the birthplace of limb reattachment.

Therefore, previously, they often had to discard a large number of animal models due to issues with the quality of the vascular and nerve anastomosis.

Even so, they had to continue using mice as models because they had identified gene segments that affect the survival and axonal growth of retinal ganglion cells in mice. It had taken ten years to find these gene segments, and their discovery was partly due to luck.

Changing the type of experimental animal would mean having to search for similar gene segments again, and even if the team were prepared to spend another decade, success was still highly uncertain.

Sometimes, the success of scientific research has multiple causes—with diligence, persistence, inspiration, luck, and more all playing a part.

Compared with the already identified genetic segments, the quality of the vascular and nerve anastomosis in eyeballs is something that can be improved, a minor flaw. Now, Claus’s team has found a shortcut by directly having Yang Ping perform eye transplantation surgeries on mice to create experimental models.

The few models they once considered to be of high quality pale in comparison to the models now made by Yang Ping, which were only crudely made.

The patient with hemisphere brain surgery had a very stable postoperative recovery, all thanks to Yang Ping’s exquisite surgical skills. John Ansen used the surgical video as a teaching tool for neurosurgery.

They broke the video’s procedures down into several hundred standard movements, then used a computer to analyze and refine them, finally extracting some standardized movements for training each doctor.

In the United States, Yang Ping did not stay for long. He declined invitations from Woodhead and Griffin and didn’t even have time to visit Robert’s base at Long Island Clinic.

The day after completing the surgery, Yang Ping and Robert flew back to China from the United States.

--

By now, a week had passed since Yang Ping’s paper submission.

In Berlin, Germany, at Manstein’s Villa.

The German Professor had already consumed dozens of cups of coffee. He stretched languidly and walked to the window, pulled back the curtains, opened the window, and was greeted by a rush of fresh air.

"This damn guy, making me stay up until morning," Manstein cursed, then took a deep breath as the first light of dawn was visible in the distance. The Professor had indeed pulled an all-nighter, staying awake from five in the afternoon until now without so much as a wink of sleep.

It was all because of a Chinese young man named Yang Ping and his damn papers.

As Professor Manstein had reviewed Yang Ping’s manuscript last time, he opened his mailbox, recognized the familiar name, and out of curiosity clicked on the email, which led him to pull an all-nighter.

While reading the paper, the German Professor simultaneously checked references, interspersed with drinking coffee and bathroom breaks, not realizing that he had stayed up until the next morning.

This genius German Professor had never seen such imaginative research; the Skin Expansion Technology within had shattered his understanding. Professor Mainshtan keenly predicted that this seemingly modest paper would mark the dawn of a new era.

When it came to Skin Expansion Technology, Professor Mainshtan had the most authority, as it was his original invention. Yet, now he felt like he had merely coined a catchy medical term for someone else’s use.

His own technology wasn’t true expansion technology, but Yang Ping’s was the real deal.

Apart from borrowing the term "expansion technology," Yang Ping’s approach was entirely different from Mainshtan’s, from theory to experiment.

Mainshtan’s Skin Expansion Technology involved taking epidermal cells and dermal cells and culturing them externally. After the cells divided, their numbers increased exponentially, but essentially, they were still scattered cultures.

All Mainshtan did was add cell paving technology to the scattered cells, allowing epidermal cells to form one layer, and dermal cells another, creating a semblance of a skin layer containing both dermis and epidermis.

Yang Ping’s Skin Expansion Technology, on the other hand, was completely different; it was a somatic cell replication technique, using a small piece of human skin and expanding it through continuous replication to form a large area of skin.

This was not mere stem cell differentiation induction but a breakthrough in cell division and construction. The ability to activate, switch on, and off certain gene expressions in skin cells had been mastered.

Replicate! Clone!

What a marvelous technology, though now it appeared only in the simple context of skin.

No one can say for sure, perhaps one day this technique could be extended to any organ. For example, patients with end-stage liver failure who still have living liver cells could use these cells to replicate a whole liver. This is a great beginning.

Unable to contain his excitement, Mainshtan immediately dialed the editor of Science, Lewis, and exclaimed with fervor, "Lewis, listen to me, after I finish you only need to answer YES. The three articles you sent me must be published as soon as possible, in this issue. I guarantee they will make your journal shine; they will make you the most visionary editor in the history of Science."

"But---my Professor, it’s already been typeset. Changes now, just aren’t feasible," Lewis said with reluctance.

"I told you, you just need to answer YES. You will thank me later. No matter what it takes, even if you have to add a few pages, they must be published in this issue. To delay would be self-harm," Mainshtan was unyielding.

Lewis, who was far away in the United States, had never seen Mainshtan so animated. He did not doubt Mainshtan’s judgement, as this rare genius’s ability to assess was far beyond his own.

But to publish three articles at once, and to give one a cover story, what an exceptional honor. The journal Science had never made such a historical decision.

"But---" Lewis tried to explain further.

Mainshtan’s tone was mixed with anger:

"Too many buts will render you mediocre, Lewis. Listen, a new star will soon rise, its dazzling light will make us seem dim. If possible, let’s be the closest witnesses," Mainshtan hung up.

No one understood the value of these papers better than Mainshtan. This genius acutely sensed that the three papers were just a prelude, hiding a huge surprise.

Typically, young people who could easily obtain such research results wouldn’t be satisfied with mere skin expansion. This was just the first door they had opened. Or rather, it wasn’t even a door, just a knock.

Mainshtan pondered: The realization of this kind of Skin Expansion Technology must have cracked some key foundational technology, which just hadn’t been reflected in the paper.

This young man would likely next move towards cloning organs, using somatic cell replication to create complete organs, and he would usher in a brand-new era.

No, perhaps his experiments had already begun. In ten or twenty years, it might indeed be possible to clone organs.

Mainshtan stood by the bedside, the morning light glittering, the horizon bathed in gold.

He downed the coffee in his cup in one gulp. The world sure is vast, and today’s sunrise truly dazzling.

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