Surgery Godfather -
Chapter 1366 - 1036: System on Vacation
Chapter 1366: Chapter 1036: System on Vacation
Huang Jiacai reported a whole lot, but actually, Yang Ping hardly listened, as his mind wasn’t really on these matters, but rather pondering over his own research topic.
Anyway, Huang Jiacai is reliable in handling tasks, and after his report, Yang Ping merely nodded symbolically.
After Huang Jiacai left, Yang Ping resumed thinking about his research subject. Brian is extraordinarily accomplished in immunology, with some laboratory methodologies that are currently the most advanced in the world in the field of immunology. During this period, through intentional and casual interactions with him, Yang Ping learned a great deal about immunology. This knowledge is significantly meaningful for his scientific research, with some knowledge even directly substituting the original laboratory methods, enhancing the experimental efficiency.
Yang Ping’s current tumor-related research project will definitely apply knowledge from immunology, as the modified M13 bacteriophage must not provoke the immune system, or all previous efforts would be wasted. Moreover, when marking tumor cells, a vast amount of knowledge in immunology is involved, such as understanding antigens. Research on tumor treatment inevitably cannot bypass immunology, and now with a top expert like Brian here, Yang Ping is determined to extract his knowledge to the fullest.
The modification of the M13 bacteriophage includes several major parts: transplanting the K factor onto the M13 bacteriophage, then finding a molecule that can pair with some characteristic substance on the surface of the tumor cell, using this pair of molecules for localization, recognition, and conjugation. Much like missile navigation, the modified M13 bacteriophage also needs its own navigation system, capable of recognizing and connecting with the tumor system.
The whole process is extremely complex and also involves knowledge of targeted therapy, but these difficulties cannot deter Yang Ping. Not to mention having the system, even without it, he would still face challenges head-on.
Yang Ping took this opportunity to enter the System Space to prepare for the experiment, but upon entering, he found the System Space had everything - utterly empty. What’s going on? Why is there only a pure space? The previous System Panel, equipment, and experimental subjects have all disappeared.
As Yang Ping was perplexed, a string of text appeared in the space: The system has entered a dormancy period, the duration of dormancy is indefinite, to test the host’s mastery of true knowledge and skills.
What is this situation?
Yang Ping had read many online novels before, not to say that he’s seen it all, but he had a bit of knowledge. He had never heard of a system going on strike, let alone having the pretty name of testing whether the host had truly learned knowledge and skills from the system.
Is this a test since he had implanted the system? To see if he had made good use of the system?
"System Space contraction countdown begins, 10-9-8-"
Before Yang Ping could react, the System Space began to shrink, becoming smaller and smaller, until it completely contracted to a point, forcing Yang Ping to exit the System Space.
Damn, the system is pulling this move, meaning that he now no longer has the system to use, and the duration of this period is unknown. Fortunately, he had been diligent, immersing himself in the system almost day and night since acquiring it, having read up everything inside many times, and made full use of all the functionalities of the system, exploiting the system’s value every moment. Perhaps it’s because of overdevelopment, the system is overwhelmed and now needs a rest.
The system’s unexpected dormancy was a bit of a surprise, but Yang Ping was not too saddened by it, because since the day he received the system he had been prepared for its departure. So now, the system’s temporary leave did not impact him much, at least not psychologically, as he always considered the system as a tool and was not absolutely dependent on it.
Although he temporarily had no system to use, Yang Ping’s work still proceeded as normal.
First, he began to research the modification plan for the M13 bacteriophage in his office using paper and pen. He drew an image of the M13 bacteriophage and clearly expressed its structure, marking all the parts that could be biologically disassembled and assembled. Then, looking at this picture, Yang Ping pondered where to mount the K factor and the Navigation factor.
Yang Ping found that the training in the system over this period had strengthened his thinking, memory, and concentration capabilities immensely. The System Space not only allowed him to learn knowledge but also honed his abilities. He tried several schemes to mount the K factor and navigational factor onto the M13 bacteriophage.
This step was not difficult for Yang Ping; the K factor, or kill tumor factor, was already available and had shown excellent effects in vitro. However, there was currently no suitable material for the navigation factor, which was the tricky part.
How to allow this missile to precisely attack tumor cells, Yang Ping needed to acquire extensive information about the targets of the tumor cells. Lu Xiaolu had already been working on this topic in the laboratory, and had even collected some information in this regard.
After clarifying the targets of the tumor cells, the next step would be to link these targets to the study of the navigation factor, as they must correspond with each other—the navigation factor needed to rely on these targets to identify tumor cells. Once recognition was completed, the M13 bacteriophage would bind with the tumor cells and inject the K factor into them, initiating the apoptosis of the tumor cells and completing the hunt of the tumor cells.
Without the trial-and-error opportunities in the System Space, Yang Ping could only start conducting in-depth research on the targets himself, hoping to summarize a set of theories to screen the targets, which would save a lot of time and reduce the number of trials and errors.
Yang Ping was accustomed to resting with his eyes closed. He leaned back in his chair with his eyes shut, immersed in his own thoughts, allowing his imagination to roam freely.
How to make the modified M13 bacteriophage locate the tumor cells was a challenge since different tumor cells both share similarities and exhibit clear differences. Therefore, future modifications of the M13 bacteriophage would need to be personalized for different tumor cells, making it affinity specific for a type or a group of tumor cells.
Just like the hepatitis B virus has a strong selectivity for stem cells, how could the modified M13 bacteriophage recognize the current experimental tumor cells—Sisi’s tumor cells.
Someone knocked on the door, and Yang Ping came back to reality from his thoughts: "Come in!"
It was Song Zimo who came in: "I heard that Old Zhang is suffering from severe body aches. Should we go see him?"
"Is it serious?" Yang Ping was quite worried.
Song Zimo said, "It should be quite serious. I heard he couldn’t bear it any longer. Just now, Liang Fatty, Zhang Lin, Little Five, and several others rushed to Old Zhang’s house."
"Why did those guys go see Old Zhang on their own without saying anything to us?" Song Zimo found it strange.
"Yeah, how come I didn’t get any news?" Yang Ping checked his phone, which still had battery.
Outside, a graduate student hurried by with a backpack. Song Zimo stopped him: "Where are you going?"
"I’m going to Old Zhang’s house," said the graduate student.
"What happened to Old Zhang? What’s this about not being able to bear it that Zhang Lin mentioned on the phone?" Song Zimo inquired.
The graduate student immediately replied, "Oh, he hasn’t played the ’PUBG’ game for several days now. He said he couldn’t bear it any longer and asked a few guys to go over to his place today for a big session—"
Yang Ping and Song Zimo were immediately stunned.
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