Surgery Godfather
Chapter 1342 - 1016: Outsiders

Chapter 1342: Chapter 1016: Outsiders

As for the wedding, Yang Ping and Xiao Su hardly worried about it. They continued with their normal work and child-rearing schedules, and their lives weren’t affected at all.

Originally, the couple wanted to have a simple wedding, and they did not want it to be complex, but things did not go as planned. Regardless of the aspect, no one agreed with their idea of a simple wedding. Nevertheless, they resigned to let things happen without their interference. Aside from spending some time on a wedding photoshoot, Yang Ping and Xiao Su did not concern themselves with the preparation progress of the wedding and were completely unaware of which stage it had reached.

Yang Ping went about his work as usual, performing surgeries all day, and then sitting down to rest in the doctor’s office. Song Zimo reported that the second follow-up results of the patient Fu Xiaotao with Kaposi’s disease had come out.

This case was always on Yang Ping’s mind because a question he raised overturned a long-standing medical theory, which made him realize that nothing should be beyond questioning or attempting.

Song Zimo opened the outpatient system on the computer and pulled up Fu Xiaotao’s medical records. Yang Ping reviewed each item one by one and compared them to the previous results.

After taking Sirolimus alone, Fu Xiaotao’s second follow-up results were significantly better than the first. Following this trend, his Kaposi’s disease could be cured in about a year or two. The treatment results proved that blocking the mTOR signaling pathway to treat Kaposi’s disease was very correct, while the previously accepted mechanism of Interleukin 6 turned out to be wrong.

This led Yang Ping to adjust the approach in his tumor laboratory. It wasn’t that his methods were incorrect, but more likely that the entire direction from the start was wrong. An incorrect direction means even perfect execution can yield unexpected results.

This confirmed the phrase: First get the right thing done, then get it done right.

During this period, Yang Ping reflected on his tumor experiments. Relying solely on the system was no longer possible for success. Now, he had to rely on his imagination to tackle the issues—imagination that the system could not provide, as it only offered time and resources.

In the evolutionary history of mankind, the process in which certain microbes coevolved with humans took a long time and is not something achievable in a short period. The protein structure K-factor, when introduced into the human body, is attacked by the immune system as a foreign body. K-factor does not have the potential for self-amplification, and under the assault of the immune system, its fate is inevitably doomed. Using an increased investment approach, an excessive amount of K-factor could overly activate the human immune system, posing a life risk.

However, some viruses, such as Hepatitis B and HIV, can exist in the human body for a long time without being destroyed by the immune system because they possess the ability to self-replicate and have learned to evade the immune system, passing on this evasion capability through generations.

Considering this, a thought suddenly struck Yang Ping. What if he obtained a virus, modified it to be harmless, and then integrated the K-factor with the virus to inject this new "virus" into the human body? This new virus would possess the ability to combat the human immune system while also being capable of killing tumor cells, living harmlessly in the body for a period and being ready to kill any recurring tumor cells at any moment.

After this bold idea emerged in his mind, Yang Ping immediately planned to redesign his experiments to pursue this new line of research. Having had experience treating Kaposi’s disease, he felt more confident about his bold ideas. Conducting experiments in the system space meant not worrying about consequences—the worst outcome would just be a waste of points, which wasn’t a big deal.

"Continue with Sirolimus?" Song Zimo asked.

Yang Ping nodded, "Continue it, and check liver and kidney functions every month. As long as liver and kidney functions are normal, keep administering it until cured."

"Understood," Song Zimo noted.

With nothing special happening, Yang Ping returned to his office, opened his computer, and checked for new emails. Professor Mainshtan had sent a new email.

"Respected Professor Yang Ping, hello, your research on spatial orientation genes is very popular, and it is considered an epoch-making achievement that will change medicine and change the world. It is the first successful localized cloning of human organs outside the body. It is no exaggeration to say that it heralds the era of independent organ cloning. In the future, the treatment of human organ failure will become cheap and easy, replacing organs as routinely as replacing machine components, and there will be no rejection issues. Once at a private salon of mine, several Nobel laureates in Medicine and Biology expressed a wish to accompany me to China for your wedding; they would like to meet and befriend such a great doctor as you. Moreover, we have a challenging case here---an ectocranial patient. She is the granddaughter of Mr. Brian, a Nobel laureate in Medicine. The poor little girl has not yet found a suitable chief surgeon because no one dares to undertake such surgery. Without your permission, I took the liberty of recommending you, please forgive me. The attached documents contain the information about this case."

Professor Manstein’s friend, a Nobel laureate in Medicine and Biology, has a six-year-old granddaughter who suffers from ectocranial anomaly. Her cardiac malformation surgery is extremely complex which is why, to date, he has not found a suitable doctor for his granddaughter. He has even sought doctors in the United States, where surgeons have performed many similar surgeries, but upon seeing his granddaughter, they could only shake their heads, the difficulty being greater than imagined.

Normally, the heart is located inside the thoracic cavity and is protected by the rib cage structuring the chest, but the heart of an ectocranial patient lies outside the thoracic cavity, the whole heart only separated from the outside world by a thin layer of skin, virtually equivalent to being exposed, and from the outside, the contour of the heart and even the contours of the blood vessels on the heart’s surface are clearly visible.

This exposed heart, if subjected to any accidental impact, could be fatal. Mr. Brian has been tirelessly searching for a doctor who can conduct the main surgery for his granddaughter but has not found anyone until Professor Manstein recommended Professor Yang from China.

The attachment includes a video sent by Professor Manstein, featuring the ectocranial child Chelsea. She wears a carbon fiber rigid chest protector to prevent everyday life incidents to the externally located heart. When the protector is removed and the clothes lifted, one can clearly see the prominently pulsing heart, the video reveals that the heart is only separated from the outside by a thin layer of skin.

From his office, Yang Ping stands at the door of the doctors’ office: "Everyone who hasn’t left work, come over here."

Not knowing what it is about, everyone gathers in the director’s office, and Yang Ping’s computer screen plays the video repeatedly, everyone staring at the screen hoping to catch every detail. Xia Shu, a doctoral student specializing in cardiology, finds this case particularly intriguing.

"This is a European case and it is very rare, the surgery is very challenging, and the postoperative maintenance requires high technical skills. Everyone, get familiar with this type of case, look up some information when you have time, and we can discuss it further."

Yang Ping said to everyone.

"This is a type of cardiac malformation, medically known as Cantrell’s Pentalogy, which consists of five concurrent malformations---sternal cleft, lower sternal defect, anterior diaphragmatic hernia, pericardial wall defects communicating with the abdominal cavity, and umbilical hernia over the abdominal wall defect. It’s this combination of anomalies that results in the heart being exposed outside the skin, making the surgery highly complicated. The surgery aims not only to correct the malformations but also to relocate the heart back into the chest, which involves addressing issues like the suspension of the heart and the alignment of the connected major vessels, and solving it all in one surgery is even more difficult."

"What type of Cantrell’s Pentalogy is it?"

"Type I! All five malformations are present."

"Besides, there are accompanying anomalies including dextrocardia, double outlet right ventricle, interventricular septum defect, interatrial septum defect, and pulmonary artery stenosis. The difficulty in treatment lies in how to correct these cardiac malformations and reposition the heart."

"We have no prior experience with this case, and it is such a complex case for an ectocranial."

"Do you know why our department is called the Surgical Research Institute? Because part of what we do is research-oriented; we are the first to try out new methods, our department combines research with clinical practice."

"There are not many cases like this carried out domestically; previously, combined cases from Fuwai and Anzhen might total over ten, but I have never seen such a complex one, and globally there are only about two hundred cases."

Everyone immediately began discussing the case.