Surgery Godfather
Chapter 1123 - 902: Manstein’s Ideal

Chapter 1123: Chapter 902: Manstein’s Ideal

The next morning, when Yang Ping went on rounds, little Xixi’s left limbs were already able to move. She happily played with her toys on the bed, blissfully unaware that she had nearly been left with a lifelong disability.

Professor Chen Jianliang came early to check on the surgery’s effect as well. Seeing such excellent surgical outcomes made him very happy since it was he who had admitted the patient for a consultation. He would have felt terrible if there had been any issues.

A two-year-old child’s brain can quickly return to normal once the obstruction is removed and the ischemic brain tissue is relieved, naturally resulting in the swift recovery of sensation and movement in the left side of the body.

Therefore, whether it’s for adults or children, the effectiveness of treatment for cerebrovascular ischemic diseases depends on how quickly blood supply can be restored—the faster, the better.

"Xixi can be discharged a week later," Yang Ping told Xixi’s father.

A week is enough time for vascular anastomosis to become stable in a two-year-old.

"Thank you, she can be discharged so soon?" Xixi’s father couldn’t believe it.

"Don’t worry, she can be discharged in a week. Remember, let her drink plenty of water during this time and do not let her inhale any secondhand smoke," Yang Ping cautioned them, as some things must be properly emphasized.

Not drinking enough can lead to blood thickening while nicotine from secondhand smoke can reduce blood oxygen levels and easily cause blood vessel spasms. Both can lead to blood vessel blockage.

Even though Yang Ping was confident in the quality of his vascular anastomosis, ensuring surgical success didn’t just rely on the quality of the anastomosis—there were other factors to consider as well.

Seeing Xixi recover so quickly filled her parents with joy, but Xixi’s grandmother stood to the side looking sullen and murmuring to herself, insisting that Xixi would have recovered without surgery. Of course, she only said this quietly, never in front of the doctors.

However, even if she said it in front of Yang Ping, he wouldn’t pay any attention to her, since she was neither the patient nor a family member who could make decisions for the patient. Yang Ping wouldn’t waste his time on irrelevant opinions.

Because his daughter had Moyamoya disease, Wang ChengPei, Xixi’s father, searched for information online and had a basic understanding of the condition.

He understood that without the emergency surgery, his daughter could truly have been left with permanent disabilities, so he was very grateful for the move. He specially called Guo Peihua to express his wish to thank him over a meal for the advice. If it weren’t for Guo’s suggestion, Wang ChengPei would likely not have moved—had it not been for the proximity to Sanbo Hospital, he shudders at what might have become of his daughter’s condition.

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Song Zimo and Xu Zhiliang’s visit to Europe was proceeding smoothly. Not only did August personally act as a guide, but Professor Mainshtan also actively provided as much help as possible. With assistance from these two, their tour of Europe was largely unhindered, and they were treated as honored guests by all the laboratories.

The reason they were received with such hospitality was not just due to Professor Mainshtan and August, but also because of Yang Ping’s 13 papers and the research results he presented at the academic conference.

Using this time, Song Zimo and Xu Zhiliang were able to visit virtually all of Europe’s top hospitals, medical universities, and medical laboratories.

They now had a comprehensive and in-depth understanding of the latest trends and advanced management in Europe’s medical research field, which was extremely important.

For most people, they might never have a chance to visit such laboratories in their lifetime, yet Song Zimo and Xu Zhiliang could visit freely, and they were accompanied by top experts in the laboratories throughout, who introduced them to the research and answered questions—it was quite an eye-opening experience.

Professor Mainshtan opened all of his laboratories to Song Zimo and Yang Ping.

He proposed a request to Song Zimo, hoping to replicate Yang Ping’s experiment.

Song Zimo told him that if he wanted to replicate Professor Yang’s experiment, he would have to use special protein factors from the Sanbo Laboratory. Currently, the structure and mechanism of this protein factor were confidential, but he could provide the end product for use in the replication of the experiment.

Professor Mainshtan understood that whatever this protein factor was and however it worked, as long as he could use it to replicate the experiment’s results, then Yang Ping’s theory would undoubtedly be valid.

Of course, Professor Mainshtan harbored no doubts about the authenticity of Yang Ping’s experimental results, but from a scientific standpoint, the experiment needed to be repeated. Additionally, he intended to recommend Yang Ping’s achievements for the Nobel Prize, which required replicating the experiment as well.

The significant breakthroughs that Yang Ping had achieved in the field of organ cloning had a profound influence on Professor Mainshtan’s current research topic.

Professor Mainshtan’s main research topic currently was studying spinal cord injury repair, which also had a close relation to stem cells, as his approach was to use stem cells for repairing damaged spinal cord.

He had coined a term for his theory—Original Cell Welding Repair.

If the spatial orientation factor truly existed, Mainshtan hypothesized, then it would be possible to locate the spinal cord’s spatial orientation gene, find its activator, and understand the interactions between the activator and the gene. Advancing research along this path

would enable them to control the repair of original cells in damaged spinal cords, allowing nerve cells in the spinal cord to grow towards each other from both ends of the break and then connect.

Original cell repair refers to using the same type of cells that are damaged for repair.

Original cell repair is the best method for repairing tissue damage in the human body, but unfortunately, for most tissue damage in the human body, the primary repair method is non-original cell repair.

The most common example is our skin repair. When skin is cut and a laceration occurs, scar tissue, rather than skin tissue, is the main component involved in the repair process, with only a very small amount of skin tissue participating in the repair.

If the tissue involved in repairing a skin laceration were all skin tissue, then after the skin wound healed, there would be no scars at all and it would look exactly the same as before.

There is one organ in our body that can perform original cell repair, and that is the skeleton. The repair after a fracture involves only bone tissue.

Apart from the skeleton, no other organ tissue can achieve original cell repair after damage.

In a spinal cord injury research laboratory in Berlin, Germany, Song Zimo and Xu Zhiliang were visiting.

"Spinal cord injury is just one of my many research subjects. Other topics include human anti-rejection research, brain cell ischemia tolerance research, and bloodless transplantation research of the brain and spinal cord, among others. All my research revolves around one major topic, and I hope I can fulfill this ideal," Manstein introduced.

"Professor Mainshtan’s major subject is head transplantation surgery!" August added.

Head transplantation surgery!

Song Zimo was quite surprised; Manstein was indeed a scientific eccentric, daring to take on such a challenging and highly controversial subject.

This type of surgery is highly controversial worldwide, mainly due to ethical issues.

Technically, there is not much controversy because all the head transplants that have been performed so far are pseudo-head transplants. Without solving spinal cord repair, all head transplantation surgeries are bound to fail, without exception.

Apart from the ethical controversy, the biggest technical hurdle of head transplantation surgery is spinal cord injury.

If spinal cord injury can be overcome, then head transplantation surgery would really be taking its first step.

"We severed the experimental monkeys’ spinal cords. Even if we used the thinnest and sharpest blade to sever it, all methods were unable to repair the spinal cord," Manstein said with frustration.

In fact, August and Milton were also researching the repair of spinal cord injuries. They too had severed the spinal cords of experimental monkeys and used polyethylene glycol as an adhesive to glue the spinal cord together, but it was in vain. No matter how they improved the connection method, it was simply impossible to achieve spinal cord repair.

Later, they attempted to use stem cells as a filler, hoping that it would help with the spinal cord repair, but there were no effective results.

Mainshtan’s research on this subject was completely different from theirs. He first studied original cell repair, investigating how to achieve original cell repair in human tissues after injury, which required beginning from a genetic perspective.

But he hadn’t thought of the spatial orientation gene until Yang Ping put forward this hypothesis. He then had an epiphany. However, the realization of it was exceptionally challenging, and the more he worked towards the goal, the farther it seemed.

Now, with the discovery of the spatial orientation gene in muscle tissue, Manstein’s confidence had greatly increased.

If one could discover the spinal cord’s spatial orientation gene, it might be possible to activate this gene, allowing spinal cord cells to enter an embryonic state, and begin to divide locally and then repair the damage. This possibility was completely plausible.

Manstein felt that Yang Ping’s theory on the spatial orientation gene was the most likely method to achieve spinal cord injury repair. So, to realize his own ideal, he had to cooperate with Yang Ping.

"We were very foolish before, attempting animal head transplantation surgeries without doing any spinal cord injury research, which was meaningless. What good does attaching a head do if, after vascular anastomosis, the head survives but the experimental monkey is left in a state of high quadriplegia and soon dies?"

"Later, we realized our foolishness and stopped such head transplants, turning instead to start foundational theoretical research related to it."

"But it’s too difficult. We have yet to make a breakthrough in the core area, although we made some breakthroughs in the peripheral areas. If you are interested, we can share our scientific research achievements."

"I’m referring to research on brain cell ischemic tolerance, anti-rejection, and bloodless transplantation," he added.

Mainshtan was entirely open with Song Zimo and Xu Zhiliang, sharing the results of his years of hard work.

Song Zimo understood that these research topics were actually of great significance. For instance, if progress was made in brain cell ischemia research, it would be possible to better treat cerebrovascular diseases and extend the rescue window for these illnesses.

Thus, any one of Mainshtan’s achievements was of top world-class level.

However, compared to Professor Yang’s achievements, Mainshtan’s achievements seemed much less significant. He estimated that even if all of Mainshtan’s results were combined, they would not come close to the significance of the spatial orientation gene.